Monitoring gastric residual volume (GRV), a common practice in intensive care units (ICUs), is believed to decrease the incidence of ventilator-associated pneumonia (VAP). Jean Reignier and members of the Clinical Research in Intensive Care and Sepsis (CRICS) Group sought to test this belief and published their results in the January 16, 2013, issue of The […]

Current guidelines for the management of upper gastrointestinal (GI) bleeding recommend a transfusion threshold hemoglobin (hgb) level of 7 g/dL. However, evidence for a restrictive transfusion strategy in acute GI bleeding is lacking. Càndid Villanueva and investigators in Barcelona, Spain, performed a randomized clinical trial to assess whether a restrictive versus liberal blood transfusion strategy was […]

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Intracranial pressure (ICP) monitoring is regarded as standard care for patients with severe traumatic brain injury (TBI). Nevertheless, even in high-income countries, the efficacy of ICP monitoring has been questioned. The identification of a group of intensivists in Bolivia and Ecuador who routinely manage TBI patients without ICP presented an opportunity for Randall Chestnut and […]

Severe sepsis and septic shock remain major public health threats worldwide. Broad global variations in mortality have been reported, ranging from 22% to more than 75%. In the December issue of Lancet Infectious Diseases, Society of Critical Care Medicine past-president Mitchell M. Levy and investigators from the Surviving Sepsis Campaign compared models of care and […]

Despite the increase in evidence-based guidelines for advanced cardiac life support and resuscitation care during the past decade, it is not clear whether survival and neurologic function after in-hospital cardiac arrest have improved. In the November issue of The New England Journal of Medicine, investigators with the American Heart Association’s Get with the Guidelines® (GWTG)-Resuscitation […]

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